The Power of twins: decoding the unseen information flow

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Researchers from Institute of Industrial Science, The University of Tokyo found that a mutual information estimator based on a dual reporter system successfully measured information flow to an output (bacterial chemotaxis) without needing to measure the input (extrinsic signals). This approach could be used to quantify information flow in a wide range of cellular signaling pathways, such as neural circuits and developmental processes.

2026.03.13

Press Release

The Power of twins: decoding the unseen information flow

Researchers from #UTokyo_IIS develop a mutual information estimator capable of accurately measuring information flow to biological outputs without needing input quantities

Related Researchers

KOBAYASHI Tetsuya J Professor

Quantitative Biology

Department of Informatics and Electronics
Center for Research on Engineering in Medicine and Biology (CREMeB)
Center for Dependable Socio-information Platform（DSiP）

Mathematical Informatics : Graduate School of Information Science and Technology
Electrical Engineering and Information Systems : Graduate School of Engineering