The research group of Lecturer Yukiko Matsunaga at the University of Tokyo, Institute of Industrial Science, succeeded in constructing an artificial three-dimensional (3D) microvasculature on a microdevice chip for an in vitro angiogenesis model. The model was observed non-invasively by stage-top type optical coherence tomography (OCT) system from a collaboration with SCREEN Holdings Co., Ltd. The system allows to capture the 3D structure of various tissues as well as vasculature easily and rapidly.
Journal Title : Scientific Reports
Article Title : Visualizing dynamics of angiogenic sprouting from a three-dimensional microvasculature model using stage-top optical coherence tomography
Author(s) : Haruko Takahashi, Keisuke Kato, Kenji Ueyama, Masayoshi Kobayashi, Gunwoong Baik, Yasuhiro Yukawa, Jun-ichi Suehiro, Yukiko T. Matsunaga
Abstract URL : http://www.nature.com/articles/srep42426