発表論文(2011~)

  1. Negishi H, Taniguchi T, Yanai H.
    The Interferon (IFN) Class of Cytokines and the IFN Regulatory Factor (IRF) Transcription Factor Family.
    Cold Spring Harb Perspect Biol. [Epub ahead of print]
  2. Yanai H, Taniguchi T
    Fine-tuning type I IFN signaling: A new chapter in the IFN saga.
    Cell Res. [Epub ahead of print]
  3. Hana Sarashina-Kida, Hideo Negishi, Junko Nishio, Wataru Suda, Yuki Nakajima, Mika Yasui-Kato, Keiko Iwaisako, Sujin Kang, Nobuyasu Endo, Hideyuki Yanai, Masataka Asagiri, Hiroshi Kida, Masahira Hattori, Atsushi Kumanogo, and Tadatsugu Taniguchi
    Gallbladder-derived surfactant protein D regulates gut commensal bacteria for maintaining intestinal homeostasis.
    Proc. Natl. Acad. Sci. U S A.114(38)10178-10183(2017)
  4. Tsuge M, Uchida T, Hiraga N, Kan H, Makokha GN, Abe-Chayama H, Miki D, Imamura M, Ochi H, Hayes CN, Shimozono R, Iwamura T, Narumi H, Suzuki T, Kainoh M, Taniguchi T, Chayama K.
    Development of a Novel Site-Specific Pegylated Interferon Beta for Antiviral Therapy of Chronic Hepatitis B Virus.
    Antimicrob Agents Chemother.61(6) (2017)
  5. Tomokatsu Iwamura, Hideki Narumi, Tomohiko Suzuki, Hideyuki Yanai, Katsuyuki Mori, Koji Yamashita, Yoshiaki Tsushima, Tomomi Asano, Akiko Izawa, Shinobu Momen, Kazumi Nishimura, Hiromi Tsuchiyama, Masashi Uchida, Yuji Yamashita, Kiyoshi Okano, Tadatsugu Taniguchi.
    A novel pegylated IFN-β as strong suppressor of the malignant ascites in a peritoneal metastasis model of human cancer.
    Cancer Science, 108(4) , 581-589 (2017)
  6. Yoshitaka Kimura, Asuka Inoue, Sho Hangai, Shinobu Saijo, Hideo Negishi, Junko Nishio, Sho Yamasaki, Yoichiro Iwakura, Hideyuki Yanai, and Tadatsugu Taniguchi.
    The innate immune receptor Dectin-2 mediates the phagocytosis of cancer cells by Kupffer cells for the suppression of liver metastasis.
    Proc. Natl. Acad. Sci. U S A. 49, 14097-14102 (2016).
  7. Ban T, Sato GR, Nishiyama A, Akiyama A, Takasuna M, Umehara M, Suzuki S, Ichino M, Matsunaga S, Kimura A, Kimura Y, Yanai H, Miyashita S, Kuromitsu J, Tsukahara K, Yoshimatsu K, Endo I, Yamamoto T, Hirano H, Ryo A, Taniguchi T, Tamura T..
    Lyn Kinase Suppresses the Transcriptional Activity of IRF5 in the TLR-MyD88 Pathway to Restrain the Development of Autoimmunity.
    Immunity. 2, 319-32(2016).
  8. Hangai S, Ao T, Kimura Y, Matsuki K, Kawamura T, Negishi H, Nishio J, Kodama T, Taniguchi T, Yanai H.
    PGE2 induced in and released by dying cells functions as an inhibitory DAMP.
    Proc. Natl. Acad. Sci. U S A. 14 3844-9(2016).
  9. Ryosuke Saigusa , Yoshihide Asano , Takashi Taniguchi , Takashi Yamashita ,Yohei Ichimura , Takehiro Takahashi , Tetsuo Toyama , Ayumi Yoshizaki , Koji Sugawara , Daisuke Tsuruta , Tadatsugu Taniguchi (corr-auth), Shinichi Sato
    Multi-facet contribution of the TLR4-activated IRF5 transcription factor in systemic sclerosis
    Proc. Natl. Acad. Sci. U S A. 49, 15136-41(2015)
  10. Nishio J, Baba M, Atarashi K, Tanoue T, Negishi H, Yanai H, Habu S, Hori S, Honda K and Taniguchi T.
    Requirement of full TCR repertoire for regulatory T cells to maintain intestinal homeostasis.
    Proc. Natl. Acad. Sci. U S A. 41, 12770-12775 (2015)
  11. Okazaki T, Higuchi M, Takeda K, Iwatsuki-Horimoto K, Kiso M, Miyagishi M, Yanai H, Kato A, Yoneyama M, Fujita T, Taniguchi T, Kawaoka Y, Ichijo H, Gotoh Y.
    The ASK family kinases differentially mediate induction of type I interferon and apoptosis during the antiviral response.
    Science Signaling. 8, (388):ra78 (2015)
  12. Chiba S, Ikushima H, Ueki H, Yanai H, Kimura Y, Hangai S, Nishio J, Negishi H, Tamura T, Saijo S, Iwakura Y, Taniguchi T.
    Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses.
    eLife 3. e04177 (2014).
  13. Yanai H, Taniguchi T.
    Nucleic acid sensing and beyond: virtues and vices of HMGB1.
    J. Intern. Med. 276, 444-53. (2014).
  14. Yanai H, Matsuda A, An J, Koshiba R, Nishio J, Negishi H, Ikushima H, Onoe T, Ohdan H, Yoshida N, Taniguchi T.
    Conditional ablation of HMGB1 in mice reveals its protective function against endotoxemia and bacterial infection.
    Proc. Natl. Acad. Sci. U S A. 51, 20699-704 (2013).
  15. Negishi H, Matsuki K, Endo N, Sarashina H, Miki S, Matsuda A, Fukazawa K , Taguchi-Atarashi N, Ikushima H, Yanai H, Nishio J, Honda K, Fujioka Y, Ohba Y, Noda T, Taniguchi S, Nishida E, Zhang Y, Chi H, Flavell RA, Taniguchi T.
    Beneficial innate signaling interference for anti-bacterial responses by a TLR-mediated enhancement of the MKP-IRF3 axis.
    Proc. Natl. Acad. Sci. U S A. 49, 19884-9 (2013).
  16. Ikushima H, Negishi H, Taniguchi T.
    The IRF Family Transcription Factors at the Interface of Innate and Adaptive Immune Responses.
    Cold Spring Harb Symp Quant Biol. 78, 105-116 (2013).
  17. Koshiba R, Yanai H, Matsuda A, Goto A, Nakajima A, Negishi H, Nishio J, Smale ST, Taniguchi T.
    Regulation of cooperative function of the Il12b enhancer and promoter by the interferon regulatory factors 3 and 5.
    Biochem. Biophys. Res. Commun. 430. 95-100 (2013).
  18. Negishi H, Miki S, Sarashina H, Taguchi-Atarashi N, Nakajima A, Matsuki K, Endo N, Yanai H, Nishio J, Honda K, Taniguchi T.
    Essential contribution of IRF3 to intestinal homeostasis and microbiota-mediated Tslp gene induction.
    Proc. Natl. Acad. Sci. U S A. 109, 21016-21 (2012).
  19. Yanai H, Negishi H, Taniguchi T.
    The IRF family of transcription factors: Inception, impact and implications in oncogenesis.
    Oncoimmunol. 1, 1376-1386 (2012).
  20. Yanai H, Ban T, Taniguchi T.
    High-mobility group box family of proteins: ligand and sensor for innate immunity.
    Trends. Immunol. 33, 633-640 (2012).
  21. Negishi H, Yanai H, Nakajima A, Koshiba R, Atarashi K, Matsuda A, Matsuki K, Miki S, Doi T, Aderem A, Nishio J, Smale ST, Honda K, Taniguchi T.
    Cross-interference of RLR and TLR signaling pathways modulates antibacterial T cell responses.
    Nat. Immunol. 13, 659-666 (2012).
  22. Idrus E, Nakashima T, Wang L, Hayashi M, Okamoto K, Kodama T, Tanaka N, Taniguchi T, Takayanagi H.
    The role of the BH3-only protein Noxa in bone homeostasis.
    Biochem. Biophys. Res. Commun. 410, 620-625 (2011).
  23. Yanai H, Ban T, Taniguchi T.
    Essential role of high-mobility group box proteins in nucleic acid-mediated innate immune responses.
    J. Intern. Med. 270, 301-308 (2011).
  24. Matsuda A, Ogawa M, Yanai H, Naka D, Goto A, Ao T, Tanno Y, Takeda K, Watanabe Y, Honda K, Taniguchi T.
    Generation of mice deficient in RNA-binding motif protein 3 (RBM3) and characterization of its role in innate immune responses and cell growth.
    Biochem. Biophys. Res. Commun. 411, 7-13 (2011).
  25. Yanai H, Chiba S, Ban T, Nakaima Y, Onoe T, Honda K, Ohdan H, Taniguchi T.
    Suppression of immune responses by nonimmunogenic oligodeoxynucleotides with high affinity for high-mobility group box proteins (HMGBs).
    Proc. Natl. Acad. Sci. USA 108, 11542-11547 (2011).
  26. Tsushima K, Osawa T, Yanai H, Nakajima A, Takaoka A, Manabe I, Ohba Y, Imai Y, Taniguchi T, Nagai R.
    IRF3 regulates cardiac fibrosis but not hypertrophy in mice during angiotensin II-induced hypertension.
    FASEB J. 25, 1531-1543 (2011).
  27. Atarashi K, Tanoue T, Shima T, Imaoka A, Kuwahara T, Momose Y, Cheng G, Yamasaki S, Saito T, Ohba Y, Taniguchi T, Takeda K, Hori S, Ivanov II, Umesaki Y, Itoh K, Honda K.
    Induction of colonic regulatory T cells by indigenous Clostridium species.
    Science 331, 337-341 (2011).

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