Nerves on the spot: Sensory Neurons in Human Skin Play Key Role in Pigmentation

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A research group led by the Institute of Industrial Science, The University of Tokyo, has found that sensory neurons play an important role in human skin pigmentation and physiology. Specifically, the neurons secrete a protein known as Repulsive Guidance Molecule B (RGMB), which stimulates melanocytes (the cells in skin that produce melanin, which is responsible for skin coloration). This study could lead to the development of new drugs to treat pigmentation disorders.

2022.09.21

Press Release

Nerves on the spot: Sensory Neurons in Human Skin Play Key Role in Pigmentation

A research group led by the Institute of Industrial Science, The University of Tokyo, finds that sensory neurons in human skin modulate melanocytes via the secretion of Repulsive Guidance Molecule B

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